Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery
نویسندگان
چکیده
منابع مشابه
Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery
RATIONALE Drug-induced valvular heart disease (DI-VHD) remains an under-recognized entity. PATIENT CONCERNS This report describes a heart valve replacement which was complicated by intractable systemic pulmonary arterial hypertension in a 61-year-old female with severe restrictive mitral and aortic disease. The diagnosis of valvular disease was preceded by a history of unexplained respiratory...
متن کامل[Valvular heart disease associated with benfluorex].
We report the first case of valvular heart disease due to benfluorex. A 50-year-old woman who had been taking the anorectic agent benfluorex intermittently for one year developed severe fibrosis and regurgitation of the mitral, aortic and tricuspid valves. Clinical, echocardiographic and histopathological findings were analogous to those reported with fenfluramine and dexfenfluramine. The simil...
متن کاملBenfluorex and Unexplained Valvular Heart Disease: A Case-Control Study
BACKGROUND Recent case reports suggest that benfluorex, a fenfluramine derivative used in the management of overweight diabetic patients and dyslipidemia, is associated with cardiac valve regurgitation. METHODS We conducted a case-control study. Eligible patients were those admitted in the cardiology or the cardiac surgery units of our hospital between January, 1(st) 2003 and June 30(th) 2009...
متن کاملcongenital heart disease with pulmonary hypertension; surgery or medical treatment?
pulmonary arterial hypertension (pha) is a frequent complication of congenital heart disease (chd), most commonly in systemic-to-pulmonary shunt lesions. in patients with an uncorrected left-to right shunt, pah will end up to eisenmenger’s syndrome, which is contraindication of surgery. what about patients with moderate to severe pah, who do not have criteria of eisenmenger’s syndrome; immediat...
متن کاملDrug-Induced- or Rheumatic- Valvular Heart Disease in Patients Exposed to Benfluorex?
There is a risk of misdiagnosis between benfluorex-induced VHD and acute rheumatic fever (ARF)-related VHD due to common characteristics of both etiologies. We aimed at estimating the probability for a patient exposed to benfluorex presenting with VHD to have, at the same time, a history of ARF-related VHD. Such epidemiological approach could help at reducing the risk of misdiagnosis. We used I...
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ژورنال
عنوان ژورنال: Medicine
سال: 2017
ISSN: 0025-7974
DOI: 10.1097/md.0000000000004985